Allopurinol: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

allopurinol for gout

Patients with hypertension and gout should be switched from hydrochlorothiazide to losartan (Cozaar) if possible. Low-dose aspirin should be continued if indicated, even though aspirin increases urate levels. Although fenofibrate (Tricor) reduces urate levels, changing cholesterol therapy is not recommended for gout. The effectiveness of low-dose colchicine is similar to that of high-dose colchicine with fewer adverse effects. NSAIDs and glucocorticoids are as effective as colchicine. Glucocorticoids can be given intramuscularly, intra-articularly, or orally.

Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Allopurinol is usually the first urate lowering therapy (ULT) they said recommended for gout. Sometimes starting allopurinol can trigger a gout attack. This is because some of the crystals can dislodge into the joint as they get smaller which can cause an attack.

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It is important to drink plenty of water during the day because this will help you get rid of more urate through your kidneys. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

allopurinol for gout

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 3 Mar 2024), Cerner Multum (updated 4 Mar 2024), ASHP (updated 10 Mar 2024) and others. You should avoid taking aspirin while you’re being treated see post for gout. If you’re in pain, you can take paracetamol and NSAIDs. But remember you should only take one NSAID at a time so do not take another if you have already been prescribed one to reduce the effects of gout attacks. Allopurinol is often recommended as the first choice of treatment to control gout.

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Alcohol may also decrease the effectiveness of this drug. Talk to your doctor if you are using marijuana (cannabis). Avoid driving or hazardous activity until you know how allopurinol will affect you. You may need frequent medical tests while using this medicine, even if you have no symptoms. Be careful if you drive or do anything that requires you to be alert.

Note that this list is not all-inclusive and includes only common medications that may interact with allopurinol. You should refer to the prescribing information they said for allopurinol for a complete list of interactions. This mainly occurs in people who have chronic kidney disease and have started a higher dose of allopurinol.

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But because it takes many months or even years for this to happen, you might still have gout attacks. The longer you have had high uric acid levels, the longer it will be before you stop experiencing gout attacks and for your uric acid levels to become normal. If this happens, there will be no more joint damage or gout attacks caused by these crystals, as long as you are taking allopurinol.

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