Buspar Uses, Dosage & Side Effects

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Inform your physician if you are pregnant, or if you are planning to become pregnant, or if you becomepregnant while you are taking buspirone hydrochloride tablets. Because the effects of concomitant administration of buspirone with most other psychotropic drugs have not been studied, the concomitant use of buspirone with other CNS-active drugs should be approached with caution. The bioavailability of buspirone is increased when given with food as compared to the fasted state (see CLINICAL image source PHARMACOLOGY). Consequently, patients should take buspirone in a consistent mannerwith regard to the timing of dosing; either always with or always without food. Common drug interactions of Buspar include monoamine oxidase (MAO) inhibitors (for example, isocarboxazid [Marplan]), trazodone (Desyrel), warfarin (Coumadin), erythromycin, itraconazole (Sporanox), nefazodone (Serzone) and rifampin. Buspar (buspirone) is an antianxiety agent prescribed for the treatment of anxiety.

A pharmacokinetic study in patientswith impaired hepatic or renal function demonstrated increased plasma levels and a lengthened half-lifeof buspirone. Therefore, the administration of buspirone hydrochloride tablets to patients with severehepatic or renal impairment cannot be recommended (see CLINICAL PHARMACOLOGY). Because buspirone hydrochloride tablets do not exhibit cross-tolerance with benzodiazepines and othercommon sedative/hypnotic drugs, it will not block the withdrawal syndrome often seen with cessation oftherapy with these drugs. Therefore, here before starting therapy with buspirone hydrochloride tablets, it isadvisable to withdraw patients gradually, especially patients who have been using a CNS-depressantdrug chronically, from their prior treatment. Rebound or withdrawal symptoms may occur over varyingtime periods, depending in part on the type of drug, and its effective half-life of elimination. In human and animal studies, buspirone has shown no potential for abuse or diversion and there is no evidence that it causes tolerance, or either physical or psychological dependence.

Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Store at room temperature away from light and moisture.

Grapefruit and grapefruit juice may interact with buspirone and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor. If you have switched to BuSpar from another anxiety medication, you may need to slowly decrease your dose of the other medication rather than stopping suddenly. If BuSpar does not alleviate your anxiety or you are not able to take it due to a medical condition or medication interaction, your doctor can determine the best alternative medication or form of treatment for your situation.

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The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects.

Specifically, it is a serotonin receptor agonist, which means that it increases action at serotonin receptors in your brain. Ask your healthcare professional how you should dispose of any medicine you do not use. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. After you begin taking buspirone, 1 to 2 weeks may pass before you begin to feel the effects of this medicine. This medicine comes with a patient information insert.

It works by balancing the levels of dopamine and serotonin in your brain, hormones that help regulate mood. Buspirone has moderate affinity for brain D2-dopamine receptors. Some studies do suggest thatbuspirone may have indirect effects on other neurotransmitter systems. the advantage Buspirone hydrochloride tablets are contraindicated in patients hypersensitive to buspironehydrochloride. Our Buspar Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

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